The Agency has contracted the Fraunhofer Institute to explore one potential alternative method to current aquatic toxicity testing of chemicals involving the use of fish.
The project examines whether the Fish Embryo Toxicity (FET) test, one of the most popular alternatives to acute toxicity testing, could be considered as a valid alternative to chronic fish toxicity testing when enhanced with transcriptomics measurements.
In ecotoxicological assessment, fish are used to evaluate short and long-term toxicity of chemicals in the aquatic environment. In addition, fish are important models for evaluating modes of toxicological action such as endocrine-disrupting effects in the environment.
To learn more about the framework contract, listen to our interview with Sylvia Escher from the Fraunhofer Institute and Tomasz Sobanski from ECHA’s Alternative Methods Team. They discuss priorities and upcoming research to advance non-animal testing methods that ensure chemical safety and meet regulatory requirements through our work to enhance science, knowledge and collaboration.
